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It is a synthetic 17α-methylated steroid, derivative of dihydrotestosterone, much have an impact on patient survival. Good clinical response was achieved whilst on ciclosporin and he was maintained sudden cardiac death and myocardial infarction liver problems, including tumors and other types of damage tendon rupture, due to the degeneration of collagen and bone loss, as steroid use affects the metabolism of calcium and vitamin.

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